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Creating Foldcomp Database Containing Discontinuous Domains #75

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@aidenkoloj

Hi I'm having trouble creating a foldcomp database and the problem appears to be the fact that many of my domains are discontinuous. When I compress my domains, I encounter an issue with the database querying all the structures. I found I could get around the issue by removing discontinuous domains.

When I run foldcomp compress with skip-discontinuous:
/home/gridsan/akolodziej/foldcomp compress \ -t $THREADS \ -d \ --skip-discontinuous \ $PDB_DIR \ $OUTPUT_DB

I get a functioning database, but many of domains are now not included. Are there any workarounds here so that I can include discontinuous domains in my database?

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  1. aidenkoloj commented on Jun 23, 2026

    @aidenkoloj
    Author

    tried renumbering with pdbtools, but the atom numbering is still discontinuous and raises an error.

  2. milot-mirdita commented on Jul 14, 2026

    @milot-mirdita
    Member

    We are working on this in the https://github.com/steineggerlab/foldcomp/commits/dev/ branch. This will be part of the next release

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