Effective sample size for case/control GWAS - #554
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summaryStatsQc canonicalizes per-variant N to the effective sample size 4/(1/nCase + 1/nControl) for case/control studies (counts from per-variant N_CASE/N_CONTROL columns or study nCase/nControl scalars; counts win over an explicit N, logged). Applied uniformly to the N-filter, kriging, the RSS fit, and colocboost via a shared effectiveN() helper. Default on; effectiveN=FALSE restores raw N. Quantitative traits unchanged.
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summaryStatsQc canonicalizes per-variant N to the effective sample size
4/(1/nCase + 1/nControl) for case/control studies (counts from per-variant
N_CASE/N_CONTROL columns or study nCase/nControl scalars; counts win over an
explicit N, logged). Applied uniformly to the N-filter, kriging, the RSS fit,
and colocboost via a shared effectiveN() helper. Default on; effectiveN=FALSE
restores raw N. Quantitative traits unchanged.