Skip to content
View Maryam-Allahyari's full-sized avatar
馃幆
Focusing
馃幆
Focusing

Highlights

  • Pro

Block or report Maryam-Allahyari

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Content in all repositories owned by your account will be closed.
Maximum 250 characters. Please don鈥檛 include any personal information such as legal names or email addresses. Markdown is supported. This note will only be visible to you.
Report abuse

Contact GitHub support about this user鈥檚 behavior. Learn more about reporting abuse.

Report abuse
Maryam-Allahyari/README.md

Hi, I'm Maryam 馃憢

I'm a bioinformatician in Toronto with a background in health research.

For four years I managed and analyzed data for the MASHAD cohort, a cardiovascular study of about 9,000 participants. I kept the participant data in PostgreSQL, derived nutrient patterns in Python using PCA, compared them between people with and without cardiovascular disease, and co-authored several papers along the way.

I then did a Master of Bioinformatics at the University of Guelph. My project compared the leaf microbiomes of herbarium specimens (some from 1938) with field-collected plants of a wild tomato relative. I built the workflow in Nextflow on the Digital Research Alliance of Canada HPC (SLURM), with tools for degraded DNA (leeHom, Samtools, Picard, BBMap), Kraken2 for classification and QIIME2 for diversity analysis.

Current project

Predicting cancer origin: Can gene expression and mutations tell us where a metastatic tumour started? Uses data from 570 BC Cancer patients, with scikit-learn, XGBoost and SHAP, and a Docker + Nextflow pipeline.

Right drug, right patient: Can a trial reliably show which patients a cancer drug works for? Testing subgroup and biomarker methods on simulated oncology trials with a CDISC pipeline in R (admiral, tern, bonsaiforest).

Tools

Python 路 R 路 SQL (PostgreSQL) 路 Bash 路 Nextflow 路 Docker 路 Git 路 HPC/SLURM 路 Quarto

Pinned Loading

  1. cancer-origin-prediction cancer-origin-prediction Public

    Can a tumour's genes tell us where a metastatic cancer started? Machine learning analysis of BC Cancer POG570 data (Python, scikit-learn, SHAP, Docker).

    Python

  2. right-drug-right-patient right-drug-right-patient Public

    Testing subgroup and biomarker methods on simulated oncology trials with a CDISC pipeline in R (admiral, tern, bonsaiforest).