diff --git a/.github/workflows/run-tests-bundled-esm.yml b/.github/workflows/run-tests-bundled-esm.yml
index 134cc67f..d2f65117 100644
--- a/.github/workflows/run-tests-bundled-esm.yml
+++ b/.github/workflows/run-tests-bundled-esm.yml
@@ -25,5 +25,6 @@ jobs:
         run: npm run test:bundled:esm:parallel
         env:
           TEST_REQUEST_API_KEY: ${{ secrets.TEST_REQUEST_API_KEY }}
+          TEST_PIA_REQUEST_API_KEY: ${{ secrets.TEST_PIA_REQUEST_API_KEY }}
           TEST_MEDIA_REQUEST_API_KEY: ${{ secrets.TEST_MEDIA_REQUEST_API_KEY }}
           SKIP_NETWORK_TIMEOUT_TESTS: true
diff --git a/cspell.json b/cspell.json
index df8b430d..2653f568 100644
--- a/cspell.json
+++ b/cspell.json
@@ -50,6 +50,7 @@
     "Bytespider",
     "Timespans",
     "googlequicksearchbox",
-    "cnstrc"
+    "cnstrc",
+    "iife"
   ]
 }
diff --git a/spec/src/constructorio.js b/spec/src/constructorio.js
index 4fdbcac2..989a794b 100644
--- a/spec/src/constructorio.js
+++ b/spec/src/constructorio.js
@@ -715,6 +715,105 @@ describe(`ConstructorIO${bundledDescriptionSuffix}`, () => {
       expect(instance.recommendations.options).to.have.property('sessionId').to.equal(oldSessionId);
       expect(instance.tracker.options).to.have.property('sessionId').to.equal(oldSessionId);
     });
+
+    it('Should update the client options with a new service url', () => {
+      const newServiceUrl = 'https://new-service-url.cnstrc.com';
+      const instance = new ConstructorIO({ apiKey: validApiKey });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal('https://ac.cnstrc.com');
+
+      instance.setClientOptions({
+        serviceUrl: newServiceUrl,
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal(newServiceUrl);
+    });
+
+    it('Should update the options for modules with a new service url', () => {
+      const newServiceUrl = 'https://new-service-url.cnstrc.com';
+      const instance = new ConstructorIO({ apiKey: validApiKey });
+
+      expect(instance.search.options).to.have.property('serviceUrl').to.equal('https://ac.cnstrc.com');
+      expect(instance.autocomplete.options).to.have.property('serviceUrl').to.equal('https://ac.cnstrc.com');
+      expect(instance.browse.options).to.have.property('serviceUrl').to.equal('https://ac.cnstrc.com');
+      expect(instance.recommendations.options).to.have.property('serviceUrl').to.equal('https://ac.cnstrc.com');
+      expect(instance.tracker.options).to.have.property('serviceUrl').to.equal('https://ac.cnstrc.com');
+
+      instance.setClientOptions({
+        serviceUrl: newServiceUrl,
+      });
+
+      expect(instance.search.options).to.have.property('serviceUrl').to.equal(newServiceUrl);
+      expect(instance.autocomplete.options).to.have.property('serviceUrl').to.equal(newServiceUrl);
+      expect(instance.browse.options).to.have.property('serviceUrl').to.equal(newServiceUrl);
+      expect(instance.recommendations.options).to.have.property('serviceUrl').to.equal(newServiceUrl);
+      expect(instance.tracker.options).to.have.property('serviceUrl').to.equal(newServiceUrl);
+    });
+
+    it('Should not update the client options service url with a falsy value', () => {
+      const originalServiceUrl = 'https://custom-service-url.cnstrc.com';
+      const instance = new ConstructorIO({
+        apiKey: validApiKey,
+        serviceUrl: originalServiceUrl,
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal(originalServiceUrl);
+
+      instance.setClientOptions({
+        serviceUrl: '',
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal(originalServiceUrl);
+
+      instance.setClientOptions({
+        serviceUrl: null,
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal(originalServiceUrl);
+    });
+
+    it('Should prepend https to a service url without a protocol', () => {
+      const instance = new ConstructorIO({ apiKey: validApiKey });
+
+      instance.setClientOptions({
+        serviceUrl: 'new-service-url.cnstrc.com',
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal('https://new-service-url.cnstrc.com');
+    });
+
+    it('Should strip a trailing slash from the service url', () => {
+      const instance = new ConstructorIO({ apiKey: validApiKey });
+
+      instance.setClientOptions({
+        serviceUrl: 'https://new-service-url.cnstrc.com/',
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal('https://new-service-url.cnstrc.com');
+    });
+
+    it('Should upgrade an http service url to https by default', () => {
+      const instance = new ConstructorIO({ apiKey: validApiKey });
+
+      instance.setClientOptions({
+        serviceUrl: 'http://new-service-url.cnstrc.com',
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal('https://new-service-url.cnstrc.com');
+    });
+
+    it('Should preserve an http service url when allowHttpServiceUrl is set', () => {
+      const instance = new ConstructorIO({
+        apiKey: validApiKey,
+        allowHttpServiceUrl: true,
+      });
+
+      instance.setClientOptions({
+        serviceUrl: 'http://new-service-url.cnstrc.com',
+      });
+
+      expect(instance.options).to.have.property('serviceUrl').to.equal('http://new-service-url.cnstrc.com');
+    });
   });
 
   if (bundled) {
diff --git a/src/constructorio.js b/src/constructorio.js
index c4e8cb39..7572724c 100644
--- a/src/constructorio.js
+++ b/src/constructorio.js
@@ -128,6 +128,7 @@ class ConstructorIO {
       apiKey,
       version: versionFromOptions || versionFromGlobal || computePackageVersion(),
       serviceUrl: helpers.addHTTPSToString(normalizedServiceUrl, allowHttpServiceUrl) || 'https://ac.cnstrc.com',
+      allowHttpServiceUrl,
       quizzesServiceUrl: (quizzesServiceUrl && quizzesServiceUrl.replace(/\/$/, '')) || 'https://quizzes.cnstrc.com',
       agentServiceUrl: (agentServiceUrl && agentServiceUrl.replace(/\/$/, '')) || 'https://agent.cnstrc.com',
       assistantServiceUrl: (assistantServiceUrl && assistantServiceUrl.replace(/\/$/, '')) || 'https://assistant.cnstrc.com',
@@ -177,10 +178,11 @@ class ConstructorIO {
    * @param {number} [options.sessionId] - Session ID - Will only be set in DOM-less environments
    * @param {string} [options.userId] - User ID
    * @param {boolean} [options.sendTrackingEvents] - Indicates if tracking events should be dispatched
+   * @param {string} [options.serviceUrl] - API URL endpoint (normalized to include an HTTPS protocol and strip a trailing slash)
    */
   setClientOptions(options) {
     if (Object.keys(options).length) {
-      const { apiKey, segments, testCells, sessionId, userId, sendTrackingEvents } = options;
+      const { apiKey, segments, testCells, sessionId, userId, sendTrackingEvents, serviceUrl } = options;
 
       if (apiKey) {
         this.options.apiKey = apiKey;
@@ -206,6 +208,12 @@ class ConstructorIO {
       if ('userId' in options) {
         this.options.userId = userId;
       }
+
+      if (typeof serviceUrl === 'string' && serviceUrl.length) {
+        const normalizedServiceUrl = serviceUrl.replace(/\/$/, '');
+        const formattedServiceUrl = helpers.addHTTPSToString(normalizedServiceUrl, this.options.allowHttpServiceUrl);
+        this.options.serviceUrl = formattedServiceUrl || this.options.serviceUrl;
+      }
     }
   }
 }